Description

7-(4-Chlorophenyl)-1,3-Dimethyl-5,5-Bis(trifluoromethyl)-8H-pyrimido[4,5-d]pyrimidine-2,4-dione is a high-value, structurally complex heterocyclic compound that serves as a critical advanced intermediate in modern organic synthesis. Its unique pyrimidopyrimidine core, functionalized with chlorophenyl and trifluoromethyl groups, makes it an essential building block for developing novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating new molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting kinase inhibition and other enzyme-related pathways.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Chemical Biology & Probe Development: Serves as a scaffold for creating molecular probes to study biological processes and identify new therapeutic targets.
• Material Science Research: Investigated as a potential monomer or additive for creating specialty polymers with unique thermal or optical properties.
• Contract Research & Development (CRO/CMO): Supplied to research organizations for custom synthesis projects and library generation for high-throughput screening.

Basic Information

Product Name	7-(4-Chlorophenyl)-1,3-Dimethyl-5,5-Bis(trifluoromethyl)-8H-pyrimido[4,5-d]pyrimidine-2,4-dione
CAS No.	488097-06-9
Molecular Formula	C₁₆H₉ClF₆N₄O₂
Molecular Weight	438.71 g/mol
Synonyms	7-(4-Chlorophenyl)-1,3-dimethyl-5,5-bis(trifluoromethyl)-8H-pyrimido[4,5-d]pyrimidine-2,4(1H,3H)-dione; 1,3-Dimethyl-7-(4-chlorophenyl)-5,5-bis(trifluoromethyl)-1H,3H,5H,8H-pyrimido[4,5-d]pyrimidine-2,4-dione; 488097-06-9; Pyrimido[4,5-d]pyrimidine-2,4-dione derivative; 5,5-Bis(trifluoromethyl)pyrimidopyrimidinedione
EINECS	Contact for details

Quality Control

Our 7-(4-Chlorophenyl)-1,3-Dimethyl-5,5-Bis(trifluoromethyl)-8H-pyrimido[4,5-d]pyrimidine-2,4-dione is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.