Description

5-Pyrimidinecarboxylicacid,4-(2-Chloro-6-Fluorophenyl)-1,2,3,4-Tetrahydro-6-Methyl-2-Oxo-,Methylester(9Ci) is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of new drugs, agrochemicals, and other fine chemical products where precise chemical architecture is paramount.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the research and synthesis of new drug candidates, especially for central nervous system (CNS) or anti-infective therapies.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, or insecticides, leveraging its fluorinated and chlorinated phenyl group.
• Chemical Biology & Proteomics: Acts as a specialized scaffold or probe in biochemical research for studying enzyme interactions or protein function.
• Material Science Precursor: Potential use in creating novel organic electronic materials or ligands for catalytic systems due to its conjugated pyrimidine core.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for client projects.

Basic Information

Product Name	5-Pyrimidinecarboxylicacid,4-(2-Chloro-6-Fluorophenyl)-1,2,3,4-Tetrahydro-6-Methyl-2-Oxo-,Methylester(9Ci)
CAS No.	487034-05-9
Molecular Formula	C13H12ClFN2O3
Molecular Weight	298.70 g/mol
Synonyms	Methyl 4-(2-chloro-6-fluorophenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate; 4-(2-Chloro-6-fluorophenyl)-1,2,3,4-tetrahydro-6-methyl-2-oxo-5-pyrimidinecarboxylic acid methyl ester; 487034-05-9; 5-Pyrimidinecarboxylic acid, 4-(2-chloro-6-fluorophenyl)-1,2,3,4-tetrahydro-6-methyl-2-oxo-, methyl ester; Methyl 4-(2-chloro-6-fluorophenyl)-6-methyl-2-oxo-3,4-dihydropyrimidine-5-carboxylate
EINECS	Contact for details

Quality Control

Our 5-Pyrimidinecarboxylicacid,4-(2-Chloro-6-Fluorophenyl)-1,2,3,4-Tetrahydro-6-Methyl-2-Oxo-,Methylester(9Ci) is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.