Description

4'-(3,4-Difluorophenoxy)Benzaldehyde is a high-purity, specialty aromatic aldehyde building block of significant interest in advanced organic synthesis. Its molecular structure, featuring a benzaldehyde core linked via an ether bridge to a difluorinated phenyl ring, makes it a versatile precursor for constructing complex molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the difluorophenoxy moiety can enhance biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of advanced organic electronic materials, including ligands for metal complexes and core structures for liquid crystals.
• Polymer Chemistry: Employed as a monomer or cross-linking agent in the production of specialty polymers with tailored thermal and chemical resistance properties.
• Chemical Research & Development: Utilized as a standard or starting material in academic and industrial R&D labs for method development and exploring new chemical reactions.
• Custom Synthesis & Contract Manufacturing: A critical intermediate for custom synthesis houses producing bespoke compounds for client-specific projects.

Basic Information

Product Name	4'-(3,4-Difluorophenoxy)Benzaldehyde
CAS No.	486449-90-5
Molecular Formula	C13H8F2O2
Molecular Weight	234.20 g/mol
Synonyms	4-(3,4-Difluorophenoxy)benzaldehyde; Benzaldehyde, 4-(3,4-difluorophenoxy)-; 4-(3,4-Difluorophenoxy)benzaldehyde; 3,4-Difluorophenyl 4-formylphenyl ether; [1,1'-Biphenyl]-4-carboxaldehyde, 4'-(3,4-difluorophenoxy)-
EINECS	Contact for details

Quality Control

Every batch of 4'-(3,4-Difluorophenoxy)Benzaldehyde is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.