Description

H-Gly-Gly-Gly-Gly-Gly-Nh2 Hbr is a high-purity, synthetic pentaglycine peptide derivative supplied as its hydrobromide salt. This compound is a crucial building block and model substrate in advanced biochemical research and pharmaceutical development. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in peptide synthesis, enzyme kinetics studies, and the development of novel therapeutic agents.

Application

• Peptide Synthesis Intermediate: Serves as a key fragment or spacer in the solid-phase and solution-phase synthesis of longer, complex peptide chains for research and development.
• Biochemical Research: Used as a model substrate for studying protease and peptidase enzyme activity, specificity, and inhibition kinetics.
• Pharmaceutical Development: Acts as a core structure or a component in the design and screening of peptide-based drug candidates and diagnostic agents.
• Reference Standard: Employed as a high-purity analytical standard in HPLC, LC-MS, and other chromatographic methods for quality control and method validation.
• Material Science: Investigated for the creation of bio-inspired materials, hydrogels, and surface coatings due to its polyglycine backbone.

Basic Information

Product Name	H-Gly-Gly-Gly-Gly-Gly-Nh2 Hbr
CAS No.	486449-24-5
Molecular Formula	C10H19BrN6O5
Molecular Weight	383.20 g/mol
Synonyms	Pentaglycine amide hydrobromide; Gly-Gly-Gly-Gly-Gly-NH2·HBr; H-Gly5-NH2·HBr; Glycine, glycylglycylglycylglycyl-, amide, hydrobromide; GGGGG-NH2 HBr; Polyglycine pentamer amide HBr salt; 2,5,8,11,14-Pentaazapentadecan-15-amide, 2,5,8,11,14-pentaoxo-, hydrobromide
EINECS	Contact for details

Quality Control

Our H-Gly-Gly-Gly-Gly-Gly-Nh2 Hbr is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and heavy metals. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to ensure compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. For long-term storage, consider desiccated conditions at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay (Anhydrous Basis)	95.0% - 105.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.