Description

Ethanone, 1-(2,6-Difluoro-4-Methylphenyl)- (9Ci) CAS NO 486415-01-4 is a specialized fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular scaffold, which incorporates strategically placed fluorine atoms and a reactive carbonyl group, enabling precise modifications for creating novel compounds. This intermediate is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drug candidates where the fluorine atoms can enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the difluoromethylphenyl moiety can contribute to improved efficacy and environmental profile.
• Material Science Research: Serves as a precursor for synthesizing specialized monomers or ligands used in the development of advanced polymers, liquid crystals, or functional materials.
• Organic Synthesis Reagent: Employed in academic and industrial R&D laboratories for constructing complex aromatic systems via reactions such as Friedel-Crafts acylation, nucleophilic addition, or further functional group transformations.
• Fluorine Chemistry Studies: Acts as a model compound for investigating the electronic effects and reactivity patterns of difluorinated arenes in various chemical environments.

Basic Information

Product Name	Ethanone, 1-(2,6-Difluoro-4-Methylphenyl)- (9Ci)
CAS No.	486415-01-4
Molecular Formula	C9H8F2O
Molecular Weight	170.16 g/mol
Synonyms	1-(2,6-Difluoro-4-methylphenyl)ethanone; 2',6'-Difluoro-4'-methylacetophenone; 4-Methyl-2,6-difluoroacetophenone; 2,6-Difluoro-4-methylacetophenone; 1-Acetyl-2,6-difluoro-4-methylbenzene; 2,6-Difluoro-p-methylacetophenone; (2,6-Difluoro-4-methylphenyl)ethanone
EINECS	Contact for details

Quality Control

Our Ethanone, 1-(2,6-Difluoro-4-Methylphenyl)- is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.