Description

Methyl 6-Methyl-2-Oxo-4-(1-Phenyl-3-(p-Tolyl)-1H-Pyrazol-4-Yl)-1,2,3,4-Tetrahydropyrimidine-5-Carboxylate is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 484049-00-5. This compound is valued for its role as a critical building block in the synthesis of complex heterocyclic molecules, offering significant utility in medicinal chemistry research and development. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers focused on creating novel therapeutic agents, particularly in areas requiring sophisticated pyrimidine and pyrazole-based scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates with targeted biological activity.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic entities.
• Heterocyclic Compound Synthesis: A versatile building block for constructing complex fused-ring systems containing pyrimidine and pyrazole moieties.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the life sciences industry.
• Academic Research: Utilized in university and institutional labs for exploratory organic synthesis and methodology development.
• Fine Chemical Production: Integrated into multi-step synthetic routes for the manufacture of high-value, low-volume specialty chemicals.

Basic Information

Product Name	Methyl 6-Methyl-2-Oxo-4-(1-Phenyl-3-(p-Tolyl)-1H-Pyrazol-4-Yl)-1,2,3,4-Tetrahydropyrimidine-5-Carboxylate
CAS No.	484049-00-5
Molecular Formula	C24H22N4O3
Molecular Weight	414.46 g/mol
Synonyms	Methyl 6-methyl-2-oxo-4-[1-phenyl-3-(4-methylphenyl)pyrazol-4-yl]-1,2,3,4-tetrahydropyrimidine-5-carboxylate; 4-(1-Phenyl-3-p-tolyl-1H-pyrazol-4-yl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid methyl ester; 484049-00-5; 1,2,3,4-Tetrahydropyrimidine-5-carboxylic acid, 6-methyl-2-oxo-4-[1-phenyl-3-(4-methylphenyl)-1H-pyrazol-4-yl]-, methyl ester
EINECS	Contact for details

Quality Control

Our production of Methyl 6-Methyl-2-Oxo-4-(1-Phenyl-3-(p-Tolyl)-1H-Pyrazol-4-Yl)-1,2,3,4-Tetrahydropyrimidine-5-Carboxylate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, to meet the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and related substances are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to minimize exposure to atmospheric humidity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.