Description

Ec 20 (Peptide) is a synthetic, bioactive peptide compound with defined sequence and high structural fidelity, widely utilized in life science research and pharmaceutical development. It delivers exceptional batch-to-batch consistency and functional reliability—critical for reproducible assay performance and preclinical target validation. Researchers and biopharmaceutical manufacturers rely on this material for cell-based assays, GPCR modulation studies, structure-activity relationship (SAR) profiling, and early-stage therapeutic candidate screening.

Application

• In vitro pharmacological profiling of neuropeptide receptors and ion channel modulation
• Lead optimization in peptide-based drug discovery programs
• Reference standard for analytical method development (HPLC, LC-MS, ELISA)
• Cell signaling pathway interrogation in primary neuronal and immune cell models
• Development of diagnostic immunoassays targeting endogenous peptide biomarkers
• Stability and degradation kinetics studies under physiological and stressed conditions
• Formulation excipient compatibility testing for parenteral peptide delivery systems
• Calibration material for mass spectrometry-based quantitative proteomics workflows

Basic Information

Product Name	Ec 20 (Peptide)
CAS No.	479578-27-3
Molecular Formula	C₁₀₂H₁₅₆N₂₈O₂₄
Molecular Weight	2261.5 g/mol
Synonyms	EC-20; Ec20; EC20 Peptide; [Gly²,Arg¹⁴]-Exendin-4(1–20); Exendin-4 fragment (1–20); Exendin-4(1–20)-NH₂; H-Gly-Ser-Ser-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-NH₂; Exendin-4 (1-20) amide
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request. All batches are verified for identity (HPLC retention time & MS confirmation), purity (≥98.5% by HPLC), water content (Karl Fischer, ≤5.0%), residual solvents (GC), and microbial limits (USP & Ph. Eur. compliant). Testing follows ICH Q5, Q6, and Q7 guidelines for peptide APIs.

Storage

Preserve in a tightly closed container, protected from light. Store at −20 °C for long-term stability; short-term storage (up to 30 days) may be conducted at 2–8 °C under desiccated, inert (argon or nitrogen) conditions. Due to its hygroscopic nature, minimize exposure to ambient humidity during handling. Avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time matches reference standard
Identification (MS)	[M+H]⁺ m/z = 2262.5 ± 0.5
Assay (HPLC)	≥98.5%
Single Impurity	≤0.5%
Total Impurities	≤1.5%
Water Content (KF)	≤5.0%
Residual Solvents (Acetonitrile, DCM, TFA)	Complies with ICH Q3C Class 2 limits
pH (5 mg/mL in water)	4.5–6.5
Endotoxin	<1.0 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.