Description

6-((2-(4-Chlorophenyl)-2-Oxoethyl)Thio)-1-Phenyl-1,5-Dihydro-4H-Pyrazolo[3,4-D]Pyrimidin-4-One is a high-purity, advanced pharmaceutical intermediate belonging to the pyrazolopyrimidinone class of heterocyclic compounds. This compound is of significant commercial importance for its role as a key synthetic building block in the research and development of novel therapeutic agents. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing kinase inhibitors and other targeted small-molecule drugs.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of potential drug candidates, particularly in oncology and inflammatory disease research.
• Kinase Inhibitor Development: Serves as a core scaffold for designing and synthesizing novel protein kinase inhibitors due to its privileged pyrazolo[3,4-d]pyrimidine structure.
• Biochemical Research: Used as a reference standard or a tool compound in enzymatic assays and biological screening to study signal transduction pathways.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead molecules.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for client projects.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and drug discovery methodologies.

Basic Information

Product Name	6-((2-(4-Chlorophenyl)-2-Oxoethyl)Thio)-1-Phenyl-1,5-Dihydro-4H-Pyrazolo[3,4-D]Pyrimidin-4-One
CAS No.	478247-52-8
Molecular Formula	C19H13ClN4O2S
Molecular Weight	396.85 g/mol
Synonyms	6-[(2-(4-Chlorophenyl)-2-oxoethyl)sulfanyl]-1-phenyl-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-4-one; 1-Phenyl-6-[[2-(4-chlorophenyl)-2-oxoethyl]thio]-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one; 478247-52-8; 6-((2-(4-Chlorophenyl)-2-oxoethyl)thio)-1-phenyl-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one; Pyrazolo[3,4-d]pyrimidin-4-one derivative
EINECS	Contact for details

Quality Control

Our 6-((2-(4-Chlorophenyl)-2-Oxoethyl)Thio)-1-Phenyl-1,5-Dihydro-4H-Pyrazolo[3,4-D]Pyrimidin-4-One is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing including HPLC, NMR, and MS to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting critical parameters such as assay purity and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.