Description

Ac-Gly-Asp-Tyr-Ser-His-Cys-Ser-Pro-Leu-Arg-Tyr-Tyr-Pro-Trp-Trp-Lys-Cys-Thr-Tyr-Pro-Asp-Pro-Glu-Gly-Gly-Gly-Nh2, (Disulfide Bond) Trifluoroacetate is a synthetic, high-purity peptide featuring a critical intramolecular disulfide bond that stabilizes its bioactive conformation. This compound is essential for advanced research and development in life sciences, where precise molecular structure and high purity are non-negotiable. It is primarily utilized by pharmaceutical R&D teams, biotechnology companies, and academic research institutions focused on peptide-based therapeutics, biochemical assays, and structure-activity relationship (SAR) studies.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or reference standard in the discovery and development of novel peptide-based drugs and biologics.
• Biochemical Assays: Used as a specific substrate, inhibitor, or ligand in enzymatic studies and receptor binding assays to investigate biological pathways.
• Structure-Activity Relationship (SAR) Studies: Provides a defined molecular scaffold for modifying peptide sequences to optimize potency, selectivity, and metabolic stability.
• Diagnostic Development: Can be employed in the development of diagnostic kits and immunoassays that require highly specific peptide antigens or probes.
• Academic Research: Supports fundamental research in biochemistry, molecular biology, and medicinal chemistry, particularly in studies involving protein-protein interactions.
• Quality Control & Standardization: Acts as a certified reference material (CRM) for analytical method validation and quality control in peptide manufacturing.

Basic Information

Product Name	Ac-Gly-Asp-Tyr-Ser-His-Cys-Ser-Pro-Leu-Arg-Tyr-Tyr-Pro-Trp-Trp-Lys-Cys-Thr-Tyr-Pro-Asp-Pro-Glu-Gly-Gly-Gly-Nh2, (Disulfide Bond) Trifluoroacetate
CAS No.	478188-26-0
Molecular Formula	C136H187N35O41S2 • xC2HF3O2
Molecular Weight	~3080.3 g/mol (Free base)
Synonyms	Ac-GDYSCHCSPLRYYPWWKCTYPDPEGGG-NH2 (Disulfide bond); Cyclic(Ac-GDYSCHCSPLRYYPWWKCTYPDPEGGG-NH2); [Ac-Gly1, Cys7,18(S-S)]-Peptide; TFA salt of Ac-GDYSCHCSPLRYYPWWKCTYPDPEGGG-NH2; Synthetic bioactive peptide 478188-26-0; Acetylated Gly-Asp-Tyr-Ser-His-Cys-Ser-Pro-Leu-Arg-Tyr-Tyr-Pro-Trp-Trp-Lys-Cys-Thr-Tyr-Pro-Asp-Pro-Glu-Gly-Gly-Gly-amide (Disulfide Bridge); Custom peptide sequence with intramolecular disulfide bond
EINECS	Contact for details

Quality Control

Our peptide products are manufactured under strict quality management systems to ensure batch-to-batch consistency and traceability. Each lot of Ac-Gly-Asp-Tyr-Ser-His-Cys-Ser-Pro-Leu-Arg-Tyr-Tyr-Pro-Trp-Trp-Lys-Cys-Thr-Tyr-Pro-Asp-Pro-Glu-Gly-Gly-Gly-Nh2, (Disulfide Bond) Trifluoroacetate undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing all specifications and test results are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to store desiccated under an inert atmosphere. Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Consistent with theoretical molecular weight
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Analysis	Within ±10% of theoretical values
Peptide Content	≥ 80.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.