Description

n-[3-(3-Cyanopyrazolo[1,5-A]Pyrimidin-5-Yl)Phenyl]-n-Ethylacetamide is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant commercial importance for its role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily sought by research institutions and manufacturers in the pharmaceutical and biotechnology sectors engaged in drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly kinase inhibitors and other targeted therapies.
• Biochemical Research: Used as a reference standard or a precursor in proteomics and molecular biology research to study enzyme interactions and signaling pathways.
• Organic Synthesis: Serves as a versatile scaffold for medicinal chemists to develop new chemical entities with potential biological activity.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials and commercial APIs.

Basic Information

Product Name	n-[3-(3-Cyanopyrazolo[1,5-A]Pyrimidin-5-Yl)Phenyl]-n-Ethylacetamide
CAS No.	478081-98-0
Molecular Formula	C₁₇H₁₅N₅O
Molecular Weight	305.34 g/mol
Synonyms	N-Ethyl-2-[3-(3-cyanopyrazolo[1,5-a]pyrimidin-5-yl)phenyl]acetamide; 2-[3-(3-Cyanopyrazolo[1,5-a]pyrimidin-5-yl)phenyl]-N-ethylacetamide; Acetamide, N-[3-(3-cyano-1H-pyrazolo[1,5-a]pyrimidin-5-yl)phenyl]-N-ethyl-; 478081-98-0; UNII-9J8K3A9U4Q; 9J8K3A9U4Q; CHEMBL3186472; BDBM50111257.
EINECS	Contact for details

Quality Control

Our n-[3-(3-Cyanopyrazolo[1,5-A]Pyrimidin-5-Yl)Phenyl]-n-Ethylacetamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and manufacturing. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This product is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.