Description

1-(2-[(3,4-Dichlorobenzyl)Sulfanyl]-4-Methyl-5-Pyrimidinyl)-1-Ethanone CAS NO 478041-94-0 is a high-purity, advanced pharmaceutical intermediate characterized by its specific pyrimidine-based structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting specific enzymatic pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes in drug discovery.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a precursor in multi-step synthetic routes for potential therapeutic compounds.
• Biochemical Research: Employed as a tool compound or reference standard in biochemical assays and pharmacological studies.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Agrochemical Research: Potential intermediate for the development of new crop protection agents, given its heterocyclic structure.

Basic Information

Item	Details
Product Name	1-(2-[(3,4-Dichlorobenzyl)Sulfanyl]-4-Methyl-5-Pyrimidinyl)-1-Ethanone
CAS No.	478041-94-0
Molecular Formula	C14H12Cl2N2OS
Molecular Weight	327.23 g/mol
Synonyms	1-[2-[(3,4-Dichlorophenyl)methylthio]-4-methyl-5-pyrimidinyl]ethanone; 1-(2-((3,4-Dichlorobenzyl)thio)-4-methylpyrimidin-5-yl)ethan-1-one; Ethanone, 1-[2-[(3,4-dichlorophenyl)methylthio]-4-methyl-5-pyrimidinyl]-; CAS 478041-94-0; 5-Acetyl-2-[(3,4-dichlorobenzyl)thio]-4-methylpyrimidine
EINECS	Contact for details

Quality Control

Our 1-(2-[(3,4-Dichlorobenzyl)Sulfanyl]-4-Methyl-5-Pyrimidinyl)-1-Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS). We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters to ensure compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). Keep away from heat, sparks, and open flame. For long-term storage, consider storage under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.