Description

2-Chloro-6-Fluorobenzyl 3-[2-(4-Pyridinyl)-4-Pyrimidinyl]Phenyl Ether is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound matters for its role as a critical building block in modern medicinal chemistry, enabling the development of targeted therapies. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the discovery and production of novel small-molecule drugs, particularly in oncology and other therapeutic areas requiring sophisticated heterocyclic scaffolds.

Application

• Key intermediate in the synthesis of kinase inhibitor candidates for oncology research.
• Building block for the development of novel pharmaceutical compounds targeting specific cellular pathways.
• Used in medicinal chemistry research for structure-activity relationship (SAR) studies.
• Precursor in the scale-up and process development of potential Active Pharmaceutical Ingredients (APIs).
• Reference standard for analytical method development and quality control in pharmaceutical manufacturing.
• Starting material for custom synthesis services catering to the life sciences industry.

Basic Information

Product Name	2-Chloro-6-Fluorobenzyl 3-[2-(4-Pyridinyl)-4-Pyrimidinyl]Phenyl Ether
CAS No.	478039-91-7
Molecular Formula	C22H15ClFN3O
Molecular Weight	391.83 g/mol
Synonyms	2-Chloro-6-fluorobenzyl 3-(2-(pyridin-4-yl)pyrimidin-4-yl)phenyl ether; 3-[2-(4-Pyridinyl)-4-pyrimidinyl]phenyl 2-chloro-6-fluorobenzyl ether; 478039-91-7; 2-Chloro-6-fluorobenzyl 3-(2-(4-pyridyl)pyrimidin-4-yl)phenyl ether; 3-(2-(Pyridin-4-yl)pyrimidin-4-yl)phenyl 2-chloro-6-fluorobenzyl ether
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-Fluorobenzyl 3-[2-(4-Pyridinyl)-4-Pyrimidinyl]Phenyl Ether is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with complete batch data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.