Description

4-[(Methylsulfanyl)Methyl]-2-(4-Pyridinyl)-6-(1-Pyrrolidinyl)Pyrimidine CAS NO 478031-46-8 is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure. This compound is of significant commercial interest for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of complex drug candidates, especially kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used as a versatile scaffold in structure-activity relationship (SAR) studies to optimize potency and selectivity of lead compounds.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex nitrogen-containing heterocycles due to its reactive pyrimidine and pyridine moieties.
• Contract Manufacturing (CMO): Supplied to contract research and manufacturing organizations (CROs/CMOs) for custom synthesis projects and scale-up activities.
• Biochemical Research: Potential use as a tool compound or probe in biochemical assays to study specific enzyme interactions and pathways.

Basic Information

Product Name	4-[(Methylsulfanyl)Methyl]-2-(4-Pyridinyl)-6-(1-Pyrrolidinyl)Pyrimidine
CAS No.	478031-46-8
Molecular Formula	C16H20N4S
Molecular Weight	300.42 g/mol
Synonyms	4-[(Methylthio)methyl]-2-(4-pyridinyl)-6-(1-pyrrolidinyl)pyrimidine; 2-(Pyridin-4-yl)-6-(pyrrolidin-1-yl)-4-((methylthio)methyl)pyrimidine; 4-(Methylsulfanylmethyl)-2-pyridin-4-yl-6-pyrrolidin-1-ylpyrimidine; 4-[(Methylsulfanyl)methyl]-2-(4-pyridyl)-6-(1-pyrrolidinyl)pyrimidine; 4-(Methylthiomethyl)-2-(4-pyridinyl)-6-(1-pyrrolidinyl)pyrimidine
EINECS	Contact for details

Quality Control

Our 4-[(Methylsulfanyl)Methyl]-2-(4-Pyridinyl)-6-(1-Pyrrolidinyl)Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, prolonged exposure to air, light, or moisture should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.