Description

4-Benzyloxy-2-Fluoroaniline, Hcl is an important fluorinated aromatic amine derivative, primarily used as a key building block in advanced organic synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and material science industries seeking to introduce specific fluorine and aniline functionalities into their target structures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and oncology therapeutics.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated aromatic compounds used in electronic display technologies and organic light-emitting diodes (OLEDs).
• Dye & Pigment Manufacturing: Employed in the synthesis of specialized fluorinated dyes and pigments that offer improved lightfastness and color properties.
• Polymer Modification: Acts as a monomer or functionalization agent to create specialty polymers with enhanced thermal or chemical resistance.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D labs exploring new fluorination chemistry and aniline-based coupling reactions.

Basic Information

Product Name	4-Benzyloxy-2-Fluoroaniline, Hcl
CAS No.	478014-34-5
Molecular Formula	C₁₃H₁₃ClFNO
Molecular Weight	253.70 g/mol
Synonyms	2-Fluoro-4-(phenylmethoxy)aniline hydrochloride; 4-(Benzyloxy)-2-fluoroaniline hydrochloride; 2-Fluoro-4-benzyloxyaniline HCl; Benzenemethanamine, 4-(phenylmethoxy)-2-fluoro-, hydrochloride; 4-Benzyloxy-2-fluoro-phenylamine hydrochloride; Aniline, 4-(benzyloxy)-2-fluoro-, hydrochloride; 478014-34-5
EINECS	Contact for details

Quality Control

Our 4-Benzyloxy-2-Fluoroaniline, Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.