Description

2-Chloro-4,6-dimethoxy-5-nitropyrimidine is a versatile and high-value pyrimidine derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its unique halogenated and nitrated dimethoxypyrimidine structure makes it an essential building block for constructing complex heterocyclic systems. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, including kinase inhibitors, antiviral agents, and other biologically active molecules.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and pesticides, leveraging its reactive chloro and nitro groups.
• Material Science Research: Building block for creating specialized polymers, ligands, or organic electronic materials with tailored properties.
• Chemical Biology Probes: Useful for synthesizing labeled compounds or probes for studying biological mechanisms and interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	2-Chloro-4,6-Dimethoxy-5-Nitro-Pyrimidine
CAS No.	478010-54-7
Molecular Formula	C6H6ClN3O4
Molecular Weight	219.58 g/mol
Synonyms	5-Nitro-2-chloro-4,6-dimethoxypyrimidine; 2-Chloro-4,6-dimethoxy-5-nitropyrimidine; 4,6-Dimethoxy-2-chloro-5-nitropyrimidine; 478010-54-7; Pyrimidine, 2-chloro-4,6-dimethoxy-5-nitro-; 2-Chloro-5-nitro-4,6-dimethoxypyrimidine
EINECS	Contact for details

Quality Control

Our 2-Chloro-4,6-dimethoxy-5-nitropyrimidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); ensure containers are sealed under an inert atmosphere if specified for the grade.

Specification

Item	Specification
Appearance	Off-white to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.