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4-[6-[(Methylsulfanyl)Methyl]-2-(2-Pyridinyl)-4-Pyrimidinyl]Morpholine CAS NO 477886-32-1


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CAS No.:477886-32-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

4-[6-[(Methylsulfanyl)Methyl]-2-(2-Pyridinyl)-4-Pyrimidinyl]Morpholine is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor research and development. It is essential for pharmaceutical manufacturers and R&D organizations focused on oncology, immunology, and other therapeutic areas requiring targeted small-molecule therapies.

Application

  • Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of potent kinase inhibitors and other targeted therapeutic agents.
  • Biochemical Research: Used as a reference standard or a building block in medicinal chemistry for structure-activity relationship (SAR) studies.
  • API Development: Serves as a core scaffold in the development and optimization of new drug candidates, especially in oncology pipelines.
  • Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials and commercial APIs.
  • Academic Research: Utilized in university and institutional labs for exploring new chemical entities and biological pathways.

Basic Information

Product Name 4-[6-[(Methylsulfanyl)Methyl]-2-(2-Pyridinyl)-4-Pyrimidinyl]Morpholine
CAS No. 477886-32-1
Molecular Formula C15H18N4OS
Molecular Weight 302.39 g/mol
Synonyms 4-(6-((Methylthio)methyl)-2-(pyridin-2-yl)pyrimidin-4-yl)morpholine; 4-[6-(Methylsulfanylmethyl)-2-pyridin-2-ylpyrimidin-4-yl]morpholine; 2-(4-Morpholino-6-((methylthio)methyl)pyrimidin-2-yl)pyridine; UNII-9J8I3K6V4C; 9J8I3K6V4C; BDBM50111671; AKOS025147064; CTK8G7235
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Quality Control

Our production of 4-[6-[(Methylsulfanyl)Methyl]-2-(2-Pyridinyl)-4-Pyrimidinyl]Morpholine adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, and our quality systems support development under cGMP guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Identification (HPLC) Conforms to reference
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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