Description

4-[(Methylsulfanyl)Methyl]-2-Phenyl-6-([3-(Trifluoromethyl)Phenyl]Sulfanyl)Pyrimidine CAS NO 477886-16-1 is a specialized pyrimidine derivative featuring a trifluoromethylphenyl sulfanyl group, a key structural motif valued in advanced chemical synthesis. This compound is engineered to serve as a high-value pharmaceutical intermediate or agrochemical building block, where its unique sulfur and fluorine-containing architecture imparts specific biological activity and metabolic stability. It is primarily sought by R&D and process development teams in the life sciences and crop protection industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in kinase inhibitor and antiviral therapeutic areas.
• Agrochemical Synthesis: Serves as a crucial building block for novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyrimidine core and trifluoromethyl group.
• Material Science Research: Used in the development of advanced organic electronic materials and ligands for catalysis due to its electron-deficient aromatic system.
• Chemical Biology Probe: Employed in the design of molecular probes to study enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and production under cGMP conditions.

Basic Information

Product Name	4-[(Methylsulfanyl)Methyl]-2-Phenyl-6-([3-(Trifluoromethyl)Phenyl]Sulfanyl)Pyrimidine
CAS No.	477886-16-1
Molecular Formula	C19H15F3N2S2
Molecular Weight	392.46 g/mol
Synonyms	4-[(Methylthio)methyl]-2-phenyl-6-[(3-(trifluoromethyl)phenyl)thio]pyrimidine; 2-Phenyl-4-(methylthiomethyl)-6-[3-(trifluoromethyl)phenylthio]pyrimidine; 6-((3-(Trifluoromethyl)phenyl)thio)-4-((methylthio)methyl)-2-phenylpyrimidine; 4-(Methylsulfanylmethyl)-2-phenyl-6-[3-(trifluoromethyl)phenyl]sulfanyl-pyrimidine; CAS 477886-16-1
EINECS	Contact for details

Quality Control

We maintain a strict quality management system to ensure batch-to-batch consistency and high purity for research and development applications. Our standard grade for this intermediate typically meets a purity specification of ≥95% (by HPLC), with higher purity grades available upon request. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and process documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.