Description

2-(3-Chlorophenyl)-4-(4-Methoxyphenyl)-6-(4-Methylpiperazino)-5-Pyrimidinecarbonitrile is a high-value, multi-substituted pyrimidine derivative serving as a critical synthetic intermediate in advanced pharmaceutical research and development. This compound is engineered to provide a versatile chemical scaffold for constructing complex molecules with targeted biological activity. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of kinase inhibitors and other small-molecule therapeutic candidates targeting various disease pathways.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators due to its bioactive pyrimidine core.
• Chemical Biology Probe: Serves as a precursor for creating molecular probes to study enzyme function and cellular signaling mechanisms.
• Material Science: Potential intermediate in the synthesis of organic electronic materials and advanced polymers with specialized properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring complex heterocyclic chemistry.

Basic Information

Product Name	2-(3-Chlorophenyl)-4-(4-Methoxyphenyl)-6-(4-Methylpiperazino)-5-Pyrimidinecarbonitrile
CAS No.	477873-09-9
Molecular Formula	C23H22ClN5O
Molecular Weight	419.91 g/mol
Synonyms	5-Cyano-2-(3-chlorophenyl)-4-(4-methoxyphenyl)-6-(4-methyl-1-piperazinyl)pyrimidine; 2-(3-Chlorophenyl)-4-(4-methoxyphenyl)-6-(4-methylpiperazin-1-yl)pyrimidine-5-carbonitrile; 477873-09-9; 6-(4-Methylpiperazino)-2-(3-chlorophenyl)-4-(4-methoxyphenyl)-5-pyrimidinecarbonitrile; 2-(3-Chloro-phenyl)-4-(4-methoxy-phenyl)-6-(4-methyl-piperazin-1-yl)-pyrimidine-5-carbonitrile
EINECS	Contact for details

Quality Control

Every batch of 2-(3-Chlorophenyl)-4-(4-Methoxyphenyl)-6-(4-Methylpiperazino)-5-Pyrimidinecarbonitrile is manufactured under a strict quality management system. We provide comprehensive analytical documentation, including HPLC, NMR, and MS data, to verify identity and purity. Certificates of Analysis (COA) are available for each lot, ensuring full traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (IR)	Spectrum matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.