Description

4-Chloro-2-(3-Chlorophenyl)-6-(4-Methoxyphenyl)-5-Pyrimidinecarbonitrile is a high-value, multi-substituted pyrimidine derivative serving as a critical synthetic intermediate in advanced organic chemistry. This compound matters for its role as a versatile building block in the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to construct complex heterocyclic systems.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of kinase inhibitors and other small-molecule therapeutic candidates.
• Agrochemical Research: Building block for developing new herbicides, fungicides, and plant growth regulators with novel modes of action.
• Material Science: Used in the research and development of organic electronic materials, such as OLED (Organic Light-Emitting Diode) components.
• Chemical Biology: Serves as a molecular scaffold for creating probes and tool compounds to study biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.
• Academic & Institutional Research: Utilized in university and government labs for fundamental studies in heterocyclic and medicinal chemistry.

Basic Information

Item	Details
Product Name	4-Chloro-2-(3-Chlorophenyl)-6-(4-Methoxyphenyl)-5-Pyrimidinecarbonitrile
CAS No.	477873-08-8
Molecular Formula	C18H11Cl2N3O
Molecular Weight	356.21 g/mol
Synonyms	5-Pyrimidinecarbonitrile, 4-chloro-2-(3-chlorophenyl)-6-(4-methoxyphenyl)-; 4-Chloro-2-(3-chlorophenyl)-6-(4-methoxyphenyl)pyrimidine-5-carbonitrile; 2-(3-Chlorophenyl)-4-chloro-6-(4-methoxyphenyl)-5-cyanopyrimidine; 4-Chloro-2-(3-chlorophenyl)-6-(p-methoxyphenyl)-5-pyrimidinecarbonitrile; CAS 477873-08-8
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-(3-Chlorophenyl)-6-(4-Methoxyphenyl)-5-Pyrimidinecarbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.