Description

n-Isopropyl-6-[(Phenylsulfonyl)Methyl]-2-(3-Pyridinyl)-4-Pyrimidinamine is a high-purity, advanced pharmaceutical intermediate designed for research and development. This compound is critical for medicinal chemists seeking to develop novel therapeutic agents, particularly in kinase inhibitor programs. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of targeted small molecule drugs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel kinase inhibitors for oncology and inflammatory disease research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for drug discovery projects.
• Biochemical Assay Development: Serves as a reference standard or probe molecule in high-throughput screening and enzymatic assays.
• Academic Research: Employed in university and institutional labs for studying heterocyclic chemistry and sulfonamide-based molecular interactions.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client pipelines.

Basic Information

Product Name	n-Isopropyl-6-[(Phenylsulfonyl)Methyl]-2-(3-Pyridinyl)-4-Pyrimidinamine
CAS No.	477867-21-3
Molecular Formula	C19H20N4O2S
Molecular Weight	368.45 g/mol
Synonyms	6-[(Phenylsulfonyl)methyl]-2-(3-pyridinyl)-N-(1-methylethyl)-4-pyrimidinamine; 4-Pyrimidinamine, N-(1-methylethyl)-6-[(phenylsulfonyl)methyl]-2-(3-pyridinyl)-; 477867-21-3; n-Isopropyl-6-(phenylsulfonylmethyl)-2-(pyridin-3-yl)pyrimidin-4-amine
EINECS	Contact for details

Quality Control

Our n-Isopropyl-6-[(Phenylsulfonyl)Methyl]-2-(3-Pyridinyl)-4-Pyrimidinamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to protect this moisture-sensitive material.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.