Description

4-[(Phenylsulfonyl)Methyl]-2-(3-Pyridinyl)-6-(1-Pyrrolidinyl)Pyrimidine is a high-purity, advanced pharmaceutical intermediate and research chemical with a complex heterocyclic structure. This compound is valued for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of potential drug candidates, especially for kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in early-stage drug discovery programs.
• Biochemical Tool Compound: Employed in vitro and in vivo to study biological pathways and validate novel therapeutic targets.
• Fine Chemical Synthesis: Acts as a specialized building block for constructing complex molecules in custom synthesis and contract manufacturing.
• Academic Research: Utilized in university and institutional labs for methodological development in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	4-[(Phenylsulfonyl)Methyl]-2-(3-Pyridinyl)-6-(1-Pyrrolidinyl)Pyrimidine
CAS No.	477867-19-9
Molecular Formula	C21H22N4O2S
Molecular Weight	394.49 g/mol
Synonyms	4-[(Phenylsulfonyl)methyl]-2-(pyridin-3-yl)-6-(pyrrolidin-1-yl)pyrimidine; 2-(3-Pyridinyl)-6-(1-pyrrolidinyl)-4-[(phenylsulfonyl)methyl]pyrimidine; 4-(Phenylsulfonylmethyl)-2-(3-pyridyl)-6-pyrrolidin-1-ylpyrimidine; Pyrimidine, 4-[(phenylsulfonyl)methyl]-2-(3-pyridinyl)-6-(1-pyrrolidinyl)-; CAS 477867-19-9
EINECS	Contact for details

Quality Control

Our 4-[(Phenylsulfonyl)Methyl]-2-(3-Pyridinyl)-6-(1-Pyrrolidinyl)Pyrimidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for research and pharmaceutical development. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.