Description

4-[6-[(Phenylsulfonyl)Methyl]-2-(3-Pyridinyl)-4-Pyrimidinyl]Morpholine is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound matters for its critical role as a key building block in the synthesis of novel, targeted therapeutic agents, particularly in oncology and kinase inhibitor research. Pharmaceutical R&D teams and fine chemical manufacturers need this material for developing next-generation drug candidates, where its precise molecular architecture enables specific biological interactions.

Application

• Pharmaceutical Intermediate: Primary use as a sophisticated building block in the synthesis of kinase inhibitors and other targeted small-molecule therapeutics.
• Oncology Drug Discovery: Key precursor in research and development pipelines for novel anti-cancer agents, leveraging its pyrimidine and pyridine motifs.
• Biochemical Research: Used as a reference standard or probe compound in enzymatic studies and high-throughput screening assays.
• Contract Manufacturing (CMO): Supplied to contract development and manufacturing organizations (CDMOs) for cGMP-scale production of active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in university and institutional labs for medicinal chemistry projects and structure-activity relationship (SAR) studies.
• Preclinical Development: Serves as a critical material for producing batches of candidate drugs required for pharmacokinetic and toxicology studies.

Basic Information

Product Name	4-[6-[(Phenylsulfonyl)Methyl]-2-(3-Pyridinyl)-4-Pyrimidinyl]Morpholine
CAS No.	477867-18-8
Molecular Formula	C20H20N4O3S
Molecular Weight	396.46 g/mol
Synonyms	4-[6-[(Phenylsulfonyl)methyl]-2-(pyridin-3-yl)pyrimidin-4-yl]morpholine; 4-(6-((Phenylsulfonyl)methyl)-2-(pyridin-3-yl)pyrimidin-4-yl)morpholine; 4-[6-(Phenylsulfonylmethyl)-2-(3-pyridyl)-4-pyrimidinyl]morpholine; 4-(6-((Phenylsulfonyl)methyl)-2-(3-pyridinyl)-4-pyrimidinyl)morpholine; UNII-9F2Q8V8J6R; 9F2Q8V8J6R; BDBM50157885; AKOS025310991; ZINC00025310991
EINECS	Contact for details

Quality Control

Our 4-[6-[(Phenylsulfonyl)Methyl]-2-(3-Pyridinyl)-4-Pyrimidinyl]Morpholine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for pharmaceutical R&D and cGMP manufacturing. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); ensure the container is kept sealed in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.