Description

4-([(4-Chlorophenyl)Sulfanyl]Methyl)-2-Phenyl-6-(1-Pyrrolidinyl)Pyrimidine CAS NO 477867-08-6 is a specialized pyrimidine derivative, a high-value chemical intermediate designed for advanced synthesis. Its molecular architecture, featuring a chlorophenylsulfanyl methyl group and a pyrrolidinyl substituent, makes it a critical building block for creating complex molecules with targeted functionalities. This compound is essential for research and development chemists in the pharmaceutical and agrochemical sectors seeking to develop new active ingredients.

Application

This pyrimidine derivative serves as a versatile intermediate in sophisticated chemical synthesis. Its primary applications include:

• Pharmaceutical Intermediate: A key precursor in the research and development of novel drug candidates, particularly for central nervous system (CNS) targets, kinase inhibitors, and other therapeutic small molecules.
• Agrochemical Synthesis: Used in the development of new pesticides, herbicides, and fungicides, leveraging its heterocyclic core for biological activity.
• Chemical Research & Development: A valuable scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Material Science Precursor: Potential use in the synthesis of organic ligands for catalysts or advanced functional materials.

Basic Information

Product Name	4-([(4-Chlorophenyl)Sulfanyl]Methyl)-2-Phenyl-6-(1-Pyrrolidinyl)Pyrimidine
CAS No.	477867-08-6
Molecular Formula	C21H20ClN3S
Molecular Weight	381.92 g/mol
Synonyms	4-[(4-Chlorophenyl)thio]methyl-2-phenyl-6-(pyrrolidin-1-yl)pyrimidine; 2-Phenyl-4-((4-chlorophenyl)thiomethyl)-6-(1-pyrrolidinyl)pyrimidine; 4-((4-Chlorophenylthio)methyl)-2-phenyl-6-(pyrrolidin-1-yl)pyrimidine; 6-(1-Pyrrolidinyl)-2-phenyl-4-[[(4-chlorophenyl)thio]methyl]pyrimidine; CAS 477867-08-6
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for your critical R&D and scale-up processes. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment, supporting your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.