Description

2-Phenyl-4-[(Phenylsulfonyl)Methyl]-6-(1-Pyrrolidinyl)Pyrimidine is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily needed by research institutions, pharmaceutical development laboratories, and fine chemical manufacturers engaged in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the research and development of new drug candidates, especially for kinase inhibitors and other targeted therapies.
• Chemical Synthesis Building Block: Used in organic synthesis to construct complex molecular architectures due to its reactive pyrimidine and sulfonyl functional groups.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties of lead compounds.
• Process Development: Utilized in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	2-Phenyl-4-[(Phenylsulfonyl)Methyl]-6-(1-Pyrrolidinyl)Pyrimidine
CAS No.	477866-98-1
Molecular Formula	C22H23N3O2S
Molecular Weight	393.50 g/mol
Synonyms	4-[(Phenylsulfonyl)methyl]-2-phenyl-6-(pyrrolidin-1-yl)pyrimidine; 2-Phenyl-4-(phenylsulfonylmethyl)-6-(1-pyrrolidinyl)pyrimidine; 6-(1-Pyrrolidinyl)-2-phenyl-4-[(phenylsulfonyl)methyl]pyrimidine; 4-(Phenylsulfonylmethyl)-2-phenyl-6-(pyrrolidin-1-yl)pyrimidine; CAS 477866-98-1
EINECS	Contact for details

Quality Control

Our 2-Phenyl-4-[(Phenylsulfonyl)Methyl]-6-(1-Pyrrolidinyl)Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.