Description

4-([(4-Chlorophenyl)Sulfanyl]Methyl)-6-Piperidino-2-(2-Pyridinyl)Pyrimidine CAS NO 477866-90-3 is a high-purity, complex heterocyclic compound featuring a pyrimidine core substituted with piperidino, pyridinyl, and chlorophenylsulfanylmethyl groups. This molecular architecture makes it a valuable advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily utilized by pharmaceutical R&D organizations and fine chemical manufacturers engaged in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas targeting specific biological pathways.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel drug candidates, especially for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Serves as a sophisticated scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Chemical Biology Probe: Used as a tool compound to investigate biological mechanisms and enzyme interactions due to its specific heterocyclic structure.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to construct complex molecules for high-value applications.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	4-([(4-Chlorophenyl)Sulfanyl]Methyl)-6-Piperidino-2-(2-Pyridinyl)Pyrimidine
CAS No.	477866-90-3
Molecular Formula	C21H21ClN4S
Molecular Weight	396.94 g/mol
Synonyms	4-[(4-Chlorophenyl)thio]methyl-6-piperidino-2-(2-pyridinyl)pyrimidine; 6-Piperidino-2-(2-pyridinyl)-4-[[(4-chlorophenyl)thio]methyl]pyrimidine; 4-((4-Chlorophenylthio)methyl)-6-(piperidin-1-yl)-2-(pyridin-2-yl)pyrimidine; 2-(2-Pyridinyl)-4-[[(4-chlorophenyl)thio]methyl]-6-(1-piperidinyl)pyrimidine; 477866-90-3; UNII-6J3S2JX8Q4
EINECS	Contact for details

Quality Control

Our 4-([(4-Chlorophenyl)Sulfanyl]Methyl)-6-Piperidino-2-(2-Pyridinyl)Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and spectroscopic identification (NMR, MS), to ensure it meets the stringent requirements for pharmaceutical research. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided. Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.