Description

4-([(4-Chlorophenyl)Sulfanyl]Methyl)-2-(2-Pyridinyl)-6-(1-Pyrrolidinyl)Pyrimidine is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Kinase Inhibitor Development: Its pyrimidine-pyridine core structure makes it relevant for research into kinase-targeted therapies.
• Chemical Biology Probes: Employed in the development of molecular probes for studying biological processes and target validation.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing specialized compounds for clients.

Basic Information

Product Name	4-([(4-Chlorophenyl)Sulfanyl]Methyl)-2-(2-Pyridinyl)-6-(1-Pyrrolidinyl)Pyrimidine
CAS No.	477866-89-0
Molecular Formula	C20H19ClN4S
Molecular Weight	382.91 g/mol
Synonyms	4-[(4-Chlorophenyl)thio]methyl-2-(2-pyridinyl)-6-(1-pyrrolidinyl)pyrimidine; 2-Pyridin-2-yl-6-pyrrolidin-1-yl-4-[(4-chlorophenyl)sulfanylmethyl]pyrimidine; 4-((4-Chlorophenyl)thio)methyl-2-(pyridin-2-yl)-6-(pyrrolidin-1-yl)pyrimidine; 477866-89-0; 4-[(4-Chlorophenyl)sulfanylmethyl]-2-(pyridin-2-yl)-6-(pyrrolidin-1-yl)pyrimidine
EINECS	Contact for details

Quality Control

Our 4-([(4-Chlorophenyl)Sulfanyl]Methyl)-2-(2-Pyridinyl)-6-(1-Pyrrolidinyl)Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to ensure stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.