Description

N'-(7-[1-(2-Fluorophenoxy)Ethyl][1,2,4]Triazolo[1,5-A]Pyrimidin-2-Yl)-N,n-Dimethyliminoformamide is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, offering a versatile building block for creating novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new drug candidates, particularly in areas requiring sophisticated heterocyclic chemistry.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel API candidates, especially those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Serves as a crucial scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Development: Potential use as an intermediate in the research and synthesis of new-generation pesticides and herbicides, leveraging its triazolopyrimidine core.
• Biochemical Tool Compound: Used in academic and industrial research to study specific biological pathways and enzyme interactions.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing specialized, high-value chemical entities.

Basic Information

Product Name	N'-(7-[1-(2-Fluorophenoxy)Ethyl][1,2,4]Triazolo[1,5-A]Pyrimidin-2-Yl)-N,n-Dimethyliminoformamide
CAS No.	477865-53-5
Molecular Formula	C₁₈H₁₉FN₆O₂
Molecular Weight	370.38 g/mol
Synonyms	N'-(7-(1-(2-Fluorophenoxy)ethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)-N,N-dimethylformimidamide; 2-[(Dimethylamino)methylideneamino]-7-[1-(2-fluorophenoxy)ethyl]-[1,2,4]triazolo[1,5-a]pyrimidine; N,N-Dimethyl-N'-(7-(1-(2-fluorophenoxy)ethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)formamidine; CAS 477865-53-5
EINECS	Contact for details

Quality Control

Our production of N'-(7-[1-(2-Fluorophenoxy)Ethyl][1,2,4]Triazolo[1,5-A]Pyrimidin-2-Yl)-N,n-Dimethyliminoformamide adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All materials are subjected to rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. Certificates of Analysis (COA) documenting full specifications are provided with each shipment. Our quality system is designed to support cGMP compliance for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong acids and strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5% w/w
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.