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7-[1-(2-Chlorophenoxy)Ethyl][1,2,4]Triazolo[1,5-A]Pyrimidin-2-Amine CAS NO 477865-28-4


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CAS No.:477865-28-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

7-[1-(2-Chlorophenoxy)Ethyl][1,2,4]Triazolo[1,5-A]Pyrimidin-2-Amine is a high-purity, advanced pharmaceutical intermediate belonging to the fused triazolopyrimidine class of heterocyclic compounds. Its molecular architecture makes it a critical building block for the synthesis of novel active pharmaceutical ingredients (APIs) with targeted biological activity. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries seeking to develop new therapeutic or crop protection agents.

Application

  • Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammatory pathways, or infectious diseases.
  • Agrochemical Research: Used in the development of new generation fungicides, herbicides, or insecticides, leveraging the bioactivity of the triazolopyrimidine core.
  • Chemical Biology Probe: Acts as a scaffold or ligand in biochemical assays to study enzyme inhibition and understand specific biological pathways.
  • Organic Synthesis Building Block: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and the creation of diverse chemical libraries for high-throughput screening.

Basic Information

Product Name 7-[1-(2-Chlorophenoxy)Ethyl][1,2,4]Triazolo[1,5-A]Pyrimidin-2-Amine
CAS No. 477865-28-4
Molecular Formula C₁₄H₁₂ClN₅O
Molecular Weight 301.73 g/mol
Synonyms 7-[1-(2-Chlorophenoxy)ethyl]-[1,2,4]triazolo[1,5-a]pyrimidin-2-amine; 2-Amino-7-[1-(2-chlorophenoxy)ethyl][1,2,4]triazolo[1,5-a]pyrimidine; CAS 477865-28-4; 7-(1-(2-Chlorophenoxy)ethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-2-amine; [1,2,4]Triazolo[1,5-a]pyrimidin-2-amine, 7-[1-(2-chlorophenoxy)ethyl]-; 477865-28-4
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Quality Control

Every batch of 7-[1-(2-Chlorophenoxy)Ethyl][1,2,4]Triazolo[1,5-A]Pyrimidin-2-Amine is manufactured under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider under an inert atmosphere to preserve stability.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (HPLC) Conforms to reference standard
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Related Substances (HPLC) Total impurities ≤ 2.0%
Single Maximum Impurity ≤ 0.5%
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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