Description

6-Bromo-3-Hydroxy-2-[3-(Trifluoromethyl)Phenyl]-4(3H)-Quinazolinone is a high-value, multi-functional heterocyclic building block designed for advanced chemical synthesis. This compound matters for its unique molecular architecture, combining a brominated quinazolinone core with a trifluoromethylphenyl substituent, which is critical for modulating the physicochemical and biological properties of target molecules. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients, as well as by material scientists exploring advanced organic electronic materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging the bioactivity of the quinazolinone scaffold.
• Material Science: Investigated as a building block for organic semiconductors, light-emitting diodes (OLEDs), and other functional materials due to its electron-deficient structure.
• Chemical Biology: Employed as a molecular probe or tag in biochemical assays to study protein-ligand interactions.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting exploratory synthetic chemistry and medicinal chemistry programs.

Basic Information

Product Name	6-Bromo-3-Hydroxy-2-[3-(Trifluoromethyl)Phenyl]-4(3H)-Quinazolinone
CAS No.	477864-81-6
Molecular Formula	C15H8BrF3N2O2
Molecular Weight	385.14 g/mol
Synonyms	6-Bromo-3-hydroxy-2-[3-(trifluoromethyl)phenyl]-4(3H)-quinazolinone; 2-(3-(Trifluoromethyl)phenyl)-6-bromo-3-hydroxy-4(3H)-quinazolinone; 4(3H)-Quinazolinone, 6-bromo-3-hydroxy-2-[3-(trifluoromethyl)phenyl]-; 6-Bromo-2-(3-trifluoromethylphenyl)-3-hydroxy-4(3H)-quinazolinone; 6-Bromo-3-hydroxy-2-(3-trifluoromethylphenyl)quinazolin-4(3H)-one; CAS 477864-81-6
EINECS	Contact for details

Quality Control

Our 6-Bromo-3-Hydroxy-2-[3-(Trifluoromethyl)Phenyl]-4(3H)-Quinazolinone is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.