Description

4-(4-Methylphenyl)-2-Pyrimidinethiol is a specialized heterocyclic organic compound featuring a pyrimidine core substituted with a thiol group and a 4-methylphenyl moiety. This unique structure makes it a valuable building block and intermediate in advanced chemical synthesis, particularly for creating complex molecules with tailored properties. It is primarily utilized by pharmaceutical research and development teams, as well as by manufacturers of agrochemicals and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Serves as a core structure for developing new fungicides, herbicides, and plant growth regulators.
• Ligand Synthesis: Used in the preparation of metal-chelating ligands for catalysis and material science applications.
• Organic Electronics: Acts as a building block for creating conjugated molecules used in organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Biology Probe Development: Employed in designing molecular probes to study biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: Supplied to fine chemical companies for bespoke synthesis projects requiring high-purity intermediates.

Basic Information

Product Name	4-(4-Methylphenyl)-2-Pyrimidinethiol
CAS No.	477859-71-5
Molecular Formula	C11H10N2S
Molecular Weight	202.28 g/mol
Synonyms	2-Mercapto-4-(p-tolyl)pyrimidine; 4-(p-Tolyl)-2-pyrimidinethiol; 4-(4-Methylphenyl)pyrimidine-2-thiol; 2-Pyrimidinethiol, 4-(4-methylphenyl)-; 4-(4-Methylphenyl)-2-mercaptopyrimidine; 4-(p-Methylphenyl)-2-pyrimidinethiol; 4-(4-Methylphenyl)-2-thiopyrimidinone (tautomer)
EINECS	Contact for details

Quality Control

Our production of 4-(4-Methylphenyl)-2-Pyrimidinethiol adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or manufacturing requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. Allow the container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.