Description

4-Chloro-6-(4-Methoxyphenyl)-2-(3-Methylphenyl)-5-Pyrimidinecarbonitrile is a high-value, multi-substituted pyrimidine derivative that serves as a critical synthetic intermediate. Its molecular architecture, featuring chloro, cyano, and aryl substituents, makes it a versatile building block for constructing complex heterocyclic systems. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the research and development of new drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the creation of advanced fungicides, herbicides, and plant growth regulators.
• Material Science Research: Serves as a building block for organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters or charge transport materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Scale-Up: Supplied for contract research organizations (CROs) and CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Employed in university and institutional labs for methodological development in heterocyclic and medicinal chemistry.

Basic Information

Product Name	4-Chloro-6-(4-Methoxyphenyl)-2-(3-Methylphenyl)-5-Pyrimidinecarbonitrile
CAS No.	477859-03-3
Molecular Formula	C19H14ClN3O
Molecular Weight	335.79 g/mol
Synonyms	5-Pyrimidinecarbonitrile, 4-chloro-6-(4-methoxyphenyl)-2-(3-methylphenyl)-; 4-Chloro-6-(p-methoxyphenyl)-2-(m-tolyl)pyrimidine-5-carbonitrile; 2-(3-Methylphenyl)-4-chloro-6-(4-methoxyphenyl)-5-pyrimidinecarbonitrile; 4-Chloro-2-(3-methylphenyl)-6-(4-methoxyphenyl)pyrimidine-5-carbonitrile; CAS 477859-03-3
EINECS	Contact for details

Quality Control

Every batch of 4-Chloro-6-(4-Methoxyphenyl)-2-(3-Methylphenyl)-5-Pyrimidinecarbonitrile is manufactured under strict quality management protocols. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with each shipment to support your R&D and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.