Description

4-Hydroxy-6-(4-Methoxyphenyl)-2-(3-Methylphenyl)-5-Pyrimidinecarbonitrile is a high-value, multi-substituted pyrimidine derivative serving as a critical synthetic intermediate in advanced organic chemistry. Its unique molecular architecture, featuring both hydroxy and cyano functionalities on the pyrimidine core, makes it an essential building block for constructing complex heterocyclic systems. This compound is primarily utilized by research institutions and pharmaceutical development companies engaged in the discovery and synthesis of novel active pharmaceutical ingredients (APIs) and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators due to its bioactive pyrimidine scaffold.
• Material Science: Acts as a monomer or functional additive in the research of advanced polymers and organic electronic materials.
• Chemical Synthesis: Employed as a versatile building block in heterocyclic and medicinal chemistry for constructing libraries of complex molecules.
• Academic & Industrial R&D: Utilized in research laboratories for methodological studies and the exploration of new chemical reactions and pathways.

Basic Information

Product Name	4-Hydroxy-6-(4-Methoxyphenyl)-2-(3-Methylphenyl)-5-Pyrimidinecarbonitrile
CAS No.	477859-02-2
Molecular Formula	C19H15N3O2
Molecular Weight	317.34 g/mol
Synonyms	5-Cyano-4-hydroxy-6-(4-methoxyphenyl)-2-(3-methylphenyl)pyrimidine; 4-Hydroxy-6-(4-methoxyphenyl)-2-(m-tolyl)-5-pyrimidinecarbonitrile; 2-(3-Methylphenyl)-4-hydroxy-6-(4-methoxyphenyl)-5-pyrimidinecarbonitrile; 6-(4-Methoxyphenyl)-2-(3-methylphenyl)-4-oxo-1,4-dihydropyrimidine-5-carbonitrile; 4-Hydroxy-2-(3-methylphenyl)-6-(4-methoxyphenyl)pyrimidine-5-carbonitrile
EINECS	Contact for details

Quality Control

Our 4-Hydroxy-6-(4-Methoxyphenyl)-2-(3-Methylphenyl)-5-Pyrimidinecarbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.