Description

5-([4-(3-Fluoropropoxy)Phenyl]Methylene)-1,3-Dimethyl-2,4,6(1H,3H,5H)-Pyrimidinetrione is a high-purity, specialized organic compound with a complex molecular structure featuring a fluoropropoxy-substituted phenyl ring. This compound serves as a critical advanced pharmaceutical intermediate or research chemical for the development of novel therapeutic agents. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in cutting-edge drug discovery programs.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential new chemical entities (NCEs) for drug discovery.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties.
• Fluorinated Compound Synthesis: Serves as a precursor for introducing the fluoropropoxy moiety into more complex molecules, a common strategy in modern drug design.
• Biochemical Tool Compound: Potential use as a probe or inhibitor in enzymatic and receptor binding assays within academic and industrial research settings.
• Fine Chemical Production: Intermediate in the multi-step synthesis of high-value, low-volume specialty chemicals.

Basic Information

Product Name	5-([4-(3-Fluoropropoxy)Phenyl]Methylene)-1,3-Dimethyl-2,4,6(1H,3H,5H)-Pyrimidinetrione
CAS No.	477857-22-0
Molecular Formula	C₁₆H₁₇FN₂O₄
Molecular Weight	320.32 g/mol
Synonyms	5-[(4-(3-Fluoropropoxy)phenyl)methylene]-1,3-dimethylpyrimidine-2,4,6(1H,3H,5H)-trione; 1,3-Dimethyl-5-((4-(3-fluoropropoxy)phenyl)methylene)barbituric acid; 5-((4-(3-Fluoropropoxy)benzylidene)-1,3-dimethylbarbituric acid; Fluoropropoxy-substituted barbiturate derivative; CAS 477857-22-0
EINECS	Contact for details

Quality Control

Our 5-([4-(3-Fluoropropoxy)Phenyl]Methylene)-1,3-Dimethyl-2,4,6(1H,3H,5H)-Pyrimidinetrione is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC purity analysis and structural confirmation (NMR, MS), to ensure identity, potency, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.