Description

Methyl 4-(4-[4-(4-Fluorophenyl)-2-Pyrimidinyl]Phenoxy)Butanoate is a high-purity, advanced pharmaceutical intermediate characterized by its specific pyrimidine-based molecular structure. This compound is critical for research and development in medicinal chemistry, serving as a key building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical manufacturers and R&D laboratories focused on developing new therapeutic agents, particularly in areas requiring complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of complex drug candidates, especially those targeting specific biological pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities in drug discovery programs.
• API Synthesis: Serves as a building block in the production of active pharmaceutical ingredients, particularly for compounds containing fluorophenyl and pyrimidine moieties.
• Biochemical Tool Compound: May be employed in biochemical assays and as a probe to study enzyme inhibition or receptor binding mechanisms.
• Custom Synthesis: Used by fine chemical suppliers for the custom manufacturing of specialized compounds for client-specific research projects.

Basic Information

Product Name	Methyl 4-(4-[4-(4-Fluorophenyl)-2-Pyrimidinyl]Phenoxy)Butanoate
CAS No.	477856-81-8
Molecular Formula	C21H19FN2O3
Molecular Weight	366.39 g/mol
Synonyms	Methyl 4-[4-[4-(4-Fluorophenyl)-2-pyrimidinyl]phenoxy]butanoate; Butanoic acid, 4-[4-[4-(4-fluorophenyl)-2-pyrimidinyl]phenoxy]-, methyl ester; 4-[4-[4-(4-Fluorophenyl)pyrimidin-2-yl]phenoxy]butyric acid methyl ester; Methyl 4-(4-(4-(4-fluorophenyl)pyrimidin-2-yl)phenoxy)butyrate; CAS 477856-81-8
EINECS	Contact for details

Quality Control

Our Methyl 4-(4-[4-(4-Fluorophenyl)-2-Pyrimidinyl]Phenoxy)Butanoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed batch-specific results are provided to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat and incompatible materials. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.