Description

Methyl 2-(4-[4-(4-Bromophenyl)-2-Pyrimidinyl]Phenoxy)Acetate is a high-purity, advanced pharmaceutical intermediate characterized by its distinct bromophenyl and pyrimidinyl functional groups. This compound is critical for research and development in medicinal chemistry, serving as a key building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly in oncology and antiviral research.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to introduce specific bromoaryl and heterocyclic motifs into target molecules.
• API Development: Serves as a critical building block in the development and scale-up of new Active Pharmaceutical Ingredients (APIs).
• Biochemical Tool Compound: Potential use in biochemical assays and as a probe for studying biological pathways and target interactions.
• Academic & Contract Research: Essential for academic research and contract research organizations (CROs) specializing in organic and heterocyclic chemistry.

Basic Information

Product Name	Methyl 2-(4-[4-(4-Bromophenyl)-2-Pyrimidinyl]Phenoxy)Acetate
CAS No.	477856-71-6
Molecular Formula	C19H15BrN2O3
Molecular Weight	399.24 g/mol
Synonyms	Methyl [4-[4-(4-bromophenyl)pyrimidin-2-yl]phenoxy]acetate; Acetic acid, 2-[4-[4-(4-bromophenyl)-2-pyrimidinyl]phenoxy]-, methyl ester; 4'-(4-Bromophenyl)-2'-pyrimidinylphenoxyacetic Acid Methyl Ester; Methyl 2-(4-(4-(4-bromophenyl)pyrimidin-2-yl)phenoxy)acetate; Methyl 4'-[4-(4-bromophenyl)-2-pyrimidinyl]phenoxyacetate; CAS 477856-71-6
EINECS	Contact for details

Quality Control

Our Methyl 2-(4-[4-(4-Bromophenyl)-2-Pyrimidinyl]Phenoxy)Acetate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Production adheres to current industry best practices, and each lot is supported by a comprehensive Certificate of Analysis (COA). The COA includes data from multiple analytical techniques, such as HPLC, NMR, and mass spectrometry, to confirm identity, purity, and impurity profiles. We are committed to meeting the stringent requirements of pharmaceutical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.