Description

4-(4-Fluorophenyl)-6-Hydroxy-2-Phenyl-5-Pyrimidinecarbonitrile is a high-value pyrimidine derivative, a key synthetic intermediate prized for its versatile chemical functionality. This compound is essential for research and development in advanced organic synthesis, particularly in constructing complex heterocyclic scaffolds. It is primarily sought by pharmaceutical R&D teams and fine chemical manufacturers for the development of novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of potential drug candidates, especially kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators due to its bioactive pyrimidine core.
• Material Science Precursor: Serves as a starting material for creating advanced organic electronic materials and liquid crystals.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in heterocyclic and medicinal chemistry.
• Chemical Reference Standard: Used as a high-purity standard for analytical method development and quality control in related chemical production.

Basic Information

Product Name	4-(4-Fluorophenyl)-6-Hydroxy-2-Phenyl-5-Pyrimidinecarbonitrile
CAS No.	477853-95-5
Molecular Formula	C17H10FN3O
Molecular Weight	291.28 g/mol
Synonyms	5-Cyano-4-(4-fluorophenyl)-6-hydroxy-2-phenylpyrimidine; 6-Hydroxy-2,4-diphenyl-5-cyanopyrimidine (fluorinated derivative); 4-(p-Fluorophenyl)-6-hydroxy-2-phenyl-5-pyrimidinecarbonitrile; 5-Pyrimidinecarbonitrile, 4-(4-fluorophenyl)-6-hydroxy-2-phenyl-; 2-Phenyl-4-(4-fluorophenyl)-6-hydroxy-5-cyanopyrimidine; CAS 477853-95-5
EINECS	Contact for details

Quality Control

Our production of 4-(4-Fluorophenyl)-6-Hydroxy-2-Phenyl-5-Pyrimidinecarbonitrile adheres to stringent in-process controls and final batch analysis to ensure consistent high purity and reliable performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles as verified by HPLC, NMR, and mass spectrometry. Our quality system is designed to meet the exacting standards of pharmaceutical and advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.