Description

4-Hydroxy-6-(4-Methylphenyl)-2-Phenyl-5-Pyrimidinecarbonitrile is a specialized pyrimidine derivative, a key heterocyclic building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of active pharmaceutical ingredients (APIs) and high-performance materials. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting kinase inhibition or other biological pathways where the pyrimidine scaffold is active.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, leveraging its heterocyclic structure for biological activity.
• Material Science: Serves as a building block for creating advanced organic electronic materials, such as components for OLEDs or charge-transport layers.
• Chemical Synthesis: Acts as a versatile synthon for further functionalization, enabling the creation of complex molecular libraries for screening and discovery.
• Academic & Industrial R&D: Employed in research laboratories for methodological studies and the exploration of new chemical reactions involving nitrile and hydroxyl functional groups on a pyrimidine core.

Basic Information

Product Name	4-Hydroxy-6-(4-Methylphenyl)-2-Phenyl-5-Pyrimidinecarbonitrile
CAS No.	477853-90-0
Molecular Formula	C18H13N3O
Molecular Weight	287.32 g/mol
Synonyms	6-(p-Tolyl)-4-hydroxy-2-phenyl-5-pyrimidinecarbonitrile; 4-Hydroxy-6-(p-tolyl)-2-phenylpyrimidine-5-carbonitrile; 5-Cyano-6-(4-methylphenyl)-4-hydroxy-2-phenylpyrimidine; 4-Hydroxy-6-(4-methylphenyl)-2-phenyl-5-cyanopyrimidine; 2-Phenyl-6-(4-methylphenyl)-4-hydroxy-5-pyrimidinecarbonitrile; 6-(4-Methylphenyl)-4-hydroxy-2-phenyl-5-pyrimidinecarbonitrile; 4-Hydroxy-2-phenyl-6-(p-tolyl)pyrimidine-5-carbonitrile
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for purity, residual solvents, and related substances are available upon request. We adhere to strict internal quality management protocols to ensure supply reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (typically 15-25°C). This compound may be light-sensitive; prolonged exposure to light should be avoided. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.