Description

2,4-Dioxo-1-(3-Pyridinyl)-1,2,3,4-Tetrahydro-5-Pyrimidinecarbonitrile is a high-purity heterocyclic organic compound featuring a fused pyrimidine-pyridine core structure. This advanced pharmaceutical intermediate is valued for its role in the synthesis of complex active pharmaceutical ingredients (APIs) and novel chemical entities. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging its heterocyclic scaffold for bioactivity.
• Chemical Synthesis: Serves as a versatile precursor for creating more complex fused-ring systems and functionalized heterocycles in medicinal chemistry.
• Academic & R&D: Employed in university and corporate research laboratories for studying structure-activity relationships (SAR) and developing new synthetic methodologies.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials and ligands for catalysis due to its nitrogen-rich aromatic structure.

Basic Information

Product Name	2,4-Dioxo-1-(3-Pyridinyl)-1,2,3,4-Tetrahydro-5-Pyrimidinecarbonitrile
CAS No.	477853-58-0
Molecular Formula	C10H6N4O2
Molecular Weight	214.18 g/mol
Synonyms	5-Cyano-1-(pyridin-3-yl)dihydropyrimidine-2,4(1H,3H)-dione; 1-(3-Pyridinyl)-2,4-dioxo-1,2,3,4-tetrahydro-5-pyrimidinecarbonitrile; 1-(Pyridin-3-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbonitrile; 5-Cyano-1-(3-pyridyl)dihydro-2,4(1H,3H)-pyrimidinedione; 1-(3-Pyridyl)-5-cyanodihydrouracil; 477853-58-0; Dihydro-2,4(1H,3H)-pyrimidinedione, 5-cyano-1-(3-pyridinyl)-
EINECS	Contact for details

Quality Control

Our 2,4-Dioxo-1-(3-Pyridinyl)-1,2,3,4-Tetrahydro-5-Pyrimidinecarbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.