Description

6-(4-Methoxyphenyl)-2-Oxo-1,2,3,6-Tetrahydro-4-Pyrimidinecarboxylic Acid is a high-purity, advanced pharmaceutical intermediate of significant commercial interest. This compound serves as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), enabling the development of novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and process chemistry for central nervous system and anti-inflammatory targets.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates, particularly in medicinal chemistry research.
• API Synthesis: Used as a building block for constructing complex heterocyclic cores in active pharmaceutical ingredient (API) manufacturing.
• Chemical Research: Serves as a valuable reagent in academic and industrial R&D for exploring new synthetic pathways and compound libraries.
• Process Development: Employed in scaling up and optimizing synthetic routes from laboratory to pilot plant and commercial production.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	6-(4-Methoxyphenyl)-2-Oxo-1,2,3,6-Tetrahydro-4-Pyrimidinecarboxylic Acid
CAS No.	477848-92-3
Molecular Formula	C₁₂H₁₂N₂O₄
Molecular Weight	248.24 g/mol
Synonyms	4-Pyrimidinecarboxylic acid, 1,2,3,6-tetrahydro-6-(4-methoxyphenyl)-2-oxo-; 6-(4-Methoxyphenyl)-1,2,3,6-tetrahydro-2-oxo-4-pyrimidinecarboxylic acid; 6-(p-Methoxyphenyl)-2-oxo-1,2,3,6-tetrahydro-4-pyrimidinecarboxylic acid; CAS 477848-92-3
EINECS	Contact for details

Quality Control

Our 6-(4-Methoxyphenyl)-2-Oxo-1,2,3,6-Tetrahydro-4-Pyrimidinecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong acids.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.