Description

4-Chloro-6-[(Methylsulfinyl)Methyl]-2-(3-Pyridinyl)Pyrimidine is a high-purity, advanced pharmaceutical intermediate characterized by its unique pyrimidine-pyridine hybrid structure with a methylsulfinylmethyl substituent. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel, targeted therapeutic agents. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of kinase inhibitors and other small-molecule drugs, where precise chemical architecture is critical for biological activity.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitor candidates.
• Medicinal Chemistry Research: Used as a versatile scaffold in drug discovery programs for structure-activity relationship (SAR) studies and lead optimization.
• Biochemical Tool Compound: Employed in biochemical assays to study enzyme inhibition mechanisms and cellular signaling pathways.
• Contract Research & Manufacturing (CRO/CMO): Supplied to outsourcing partners for custom synthesis and process development projects.
• Academic Research: Utilized in university and institutional labs for fundamental research in heterocyclic chemistry and bioorganic synthesis.

Basic Information

Item	Details
Product Name	4-Chloro-6-[(Methylsulfinyl)Methyl]-2-(3-Pyridinyl)Pyrimidine
CAS No.	477711-31-2
Molecular Formula	C11H10ClN3OS
Molecular Weight	267.73 g/mol
Synonyms	4-Chloro-6-[(methylsulfinyl)methyl]-2-(pyridin-3-yl)pyrimidine; 2-(3-Pyridinyl)-4-chloro-6-[(methylsulfinyl)methyl]pyrimidine; 4-Chloro-6-(methylsulfinylmethyl)-2-(3-pyridyl)pyrimidine; 4-Chloro-6-((methylsulfinyl)methyl)-2-(pyridin-3-yl)pyrimidine; CAS 477711-31-2
EINECS	Contact for details

Quality Control

Our 4-Chloro-6-[(Methylsulfinyl)Methyl]-2-(3-Pyridinyl)Pyrimidine is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and internal standards. Our commitment to cGMP principles in production ensures material integrity for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic; therefore, the container should be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.