Description

3-Piperidinamine, 1-Acetyl-N,4-Dimethyl-n-1H-Pyrrolo[2,3-D]Pyrimidin-4-Yl-, (3R,4R)- (9Ci) CAS NO 477600-76-3 is a high-purity, stereochemically defined heterocyclic organic compound featuring a fused pyrrolopyrimidine core. This compound is of significant value as a key chiral intermediate or building block in advanced synthetic chemistry, particularly for the development of novel active pharmaceutical ingredients (APIs). It is primarily needed by pharmaceutical R&D organizations, contract research and manufacturing services (CRAMS) providers, and fine chemical synthesis specialists working on targeted therapies.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral building block in the synthesis of potential drug candidates, especially kinase inhibitors or other targeted small molecule therapeutics.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its complex, privileged scaffold.
• Chemical Biology Probes: Can be utilized in the development of chemical probes for studying specific biological pathways and protein functions.
• Process Chemistry Development: Employed in route scouting and scale-up optimization for the production of advanced intermediates under Good Manufacturing Practice (GMP) conditions.
• Academic Research: Used in university and institutional labs for methodological development in asymmetric synthesis and heterocyclic chemistry.
• Custom Synthesis: A starting material for contract manufacturing organizations (CMOs) offering bespoke synthesis services for client-specific molecules.

Basic Information

Product Name	3-Piperidinamine, 1-Acetyl-N,4-Dimethyl-n-1H-Pyrrolo[2,3-D]Pyrimidin-4-Yl-, (3R,4R)- (9Ci)
CAS No.	477600-76-3
Molecular Formula	C15H21N5O
Molecular Weight	287.36 g/mol
Synonyms	(3R,4R)-1-Acetyl-N,4-dimethyl-N-(1H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-3-amine; 1-[(3R,4R)-3-[(4-Dimethylamino)-1H-pyrrolo[2,3-d]pyrimidin-1-yl]-4-piperidinyl]ethanone; UNII-9K5N6V6Y8I; 477600-76-3; (3R,4R)-1-Acetyl-N,4-dimethyl-N-(1H-pyrrolo[2,3-d]pyrimidin-4-yl)-3-piperidinamine; 1-Acetyl-N,4-dimethyl-N-(1H-pyrrolo[2,3-d]pyrimidin-4-yl)-3-piperidinamine, (3R,4R)-rel-; (rel-(3R,4R))-1-Acetyl-N,4-dimethyl-N-(1H-pyrrolo[2,3-d]pyrimidin-4-yl)-3-piperidinamine
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to verify identity, purity, and stereochemical integrity. Certificates of Analysis (COA) detailing batch-specific results are available upon request. For advanced applications, we can support development under GMP-grade quality management systems.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.