Description

3-Bromo-5-(Trifluoromethyl)Benzaldehyde is a versatile and highly functionalized aromatic aldehyde building block. Its molecular structure, featuring both bromo and trifluoromethyl substituents, makes it a critical intermediate for introducing specific steric and electronic properties into target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical sectors. It is particularly valued for synthesizing advanced active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially in drug discovery programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, due to its electron-withdrawing characteristics.
• Custom Synthesis and Contract Manufacturing: A high-value starting material for fine chemical manufacturers offering bespoke synthesis services.
• Academic and R&D Laboratories: Used in methodological studies and as a standard reagent for exploring new cross-coupling and functionalization reactions.

Basic Information

Product Name	3-Bromo-5-(Trifluoromethyl)Benzaldehyde
CAS No.	477535-41-4
Molecular Formula	C8H4BrF3O
Molecular Weight	253.02 g/mol
Synonyms	3-Bromo-5-(trifluoromethyl)benzaldehyde; 5-Bromo-3-(trifluoromethyl)benzaldehyde; m-Bromo-α,α,α-trifluoro-m-tolualdehyde; Benzaldehyde, 3-bromo-5-(trifluoromethyl)-; 3-Bromo-α,α,α-trifluoro-m-tolualdehyde; 477535-41-4; 5-(Trifluoromethyl)-3-bromobenzaldehyde
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-(Trifluoromethyl)Benzaldehyde is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality parameters. Our commitment to cGMP and ISO standards ensures reliable supply for demanding applications in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert gas such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.