Description

3-(Naphthalen-1-Ylmethyl)-1H-Pyrazolo[3,4-D]Pyrimidin-4-Amine is a heterocyclic organic compound belonging to the pyrazolopyrimidine class, which serves as a critical synthetic intermediate and pharmacologically active scaffold. This compound matters for its role as a versatile building block in medicinal chemistry, enabling the development of targeted therapeutic agents. It is primarily needed by pharmaceutical R&D laboratories, biotechnology companies, and fine chemical manufacturers engaged in the synthesis of kinase inhibitors and other biologically active molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel kinase inhibitors and other small-molecule drug candidates.
• Biochemical Research: Used as a reference standard or probe compound in enzymatic assays and target validation studies.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies and lead optimization programs.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value specialty chemicals.
• Academic Research: Utilized in universities and research institutes for exploring new heterocyclic chemistry and reaction methodologies.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Product Name	3-(Naphthalen-1-Ylmethyl)-1H-Pyrazolo[3,4-D]Pyrimidin-4-Amine
CAS No.	476371-69-4
Molecular Formula	C₁₇H₁₄N₆
Molecular Weight	302.33 g/mol
Synonyms	3-(1-Naphthylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine; 3-(Naphthalen-1-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine; 1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 3-[(1-naphthalenyl)methyl]-; 476371-69-4; 3-(1-Naphthylmethyl)-4-amino-1H-pyrazolo[3,4-d]pyrimidine; 4-Amino-3-(1-naphthylmethyl)-1H-pyrazolo[3,4-d]pyrimidine
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request. Quality is assured through validated analytical methods including HPLC, NMR, and mass spectrometry to confirm identity, purity, and potency. We adhere to cGMP principles for the manufacture of pharmaceutical intermediates, ensuring traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and may require storage under an inert atmosphere or with desiccant for long-term preservation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.