Description

8-Amino-7-Isobutyl-3-Methyl-3,7-Dihydro-Purine-2,6-Dione is a high-purity, synthetically derived xanthine derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block (synthon) for the synthesis of novel therapeutic agents, particularly those targeting neurological and cardiovascular pathways. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the production of active pharmaceutical ingredients (APIs) and reference standards.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel adenosine receptor antagonists and phosphodiesterase (PDE) inhibitors.
• Neurological Research: Used in developing compounds for potential application in neurodegenerative diseases and cognitive disorders.
• Cardiovascular Drug Development: Serves as a core structure for molecules being investigated for their vasodilatory and cardioprotective effects.
• Chemical Biology: Employed as a tool compound or probe to study purinergic signaling pathways and enzyme mechanisms.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Fine Chemical Synthesis: Utilized in custom synthesis and contract manufacturing for producing specialized, high-value chemical entities.

Basic Information

Product Name	8-Amino-7-Isobutyl-3-Methyl-3,7-Dihydro-Purine-2,6-Dione
CAS No.	476294-15-2
Molecular Formula	C₁₀H₁₅N₅O₂
Molecular Weight	237.26 g/mol
Synonyms	8-Amino-7-isobutyl-3-methyl-3,7-dihydro-1H-purine-2,6-dione; 8-Amino-7-isobutyl-3-methylxanthine; 8-Amino-IBMX; 8-Amino-3-methyl-7-(2-methylpropyl)-1H-purine-2,6-dione; 8-Amino-3-methyl-7-isobutylxanthine; 8-Amino-7-(2-methylpropyl)-3-methyl-3,7-dihydro-1H-purine-2,6-dione
EINECS	Contact for details

Quality Control

Our 8-Amino-7-Isobutyl-3-Methyl-3,7-Dihydro-Purine-2,6-Dione is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes. We support development and commercial projects requiring material that meets ICH guidelines for impurities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The container should be kept tightly sealed in a dry environment to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.