Description

5-(3-(Benzyloxy)Phenyl)-5H-Pyrrolo[2,3-D]Pyrimidin-4-Amine is a high-purity, advanced pharmaceutical intermediate belonging to the pyrrolopyrimidine class of heterocyclic compounds. This compound is of significant commercial interest for its role as a key building block in the synthesis of novel, biologically active molecules, particularly kinase inhibitors. It is primarily required by research institutions and pharmaceutical companies engaged in drug discovery and development programs. The material is supplied with full analytical documentation to ensure consistency and reliability for critical synthetic pathways.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of targeted therapeutic agents, especially protein kinase inhibitors.
• Drug Discovery Research: Used in medicinal chemistry for the design, synthesis, and structure-activity relationship (SAR) studies of new chemical entities.
• Biochemical Tool Compound: Employed in vitro and in vivo to study specific biological pathways and validate novel drug targets.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in university and institutional labs for fundamental research in organic chemistry and pharmacology.

Basic Information

Product Name	5-(3-(Benzyloxy)Phenyl)-5H-Pyrrolo[2,3-D]Pyrimidin-4-Amine
CAS No.	475489-37-3
Molecular Formula	C19H16N4O
Molecular Weight	316.36 g/mol
Synonyms	4-Amino-5-(3-benzyloxyphenyl)-5H-pyrrolo[2,3-d]pyrimidine; 5-(3-Benzyloxyphenyl)-4-amino-5H-pyrrolo[2,3-d]pyrimidine; 5H-Pyrrolo[2,3-d]pyrimidin-4-amine, 5-[3-(phenylmethoxy)phenyl]-; CAS 475489-37-3; Benzyloxy Phenyl Pyrrolopyrimidine Amine; BPPPA (abbrev.); Kinase Inhibitor Intermediate BP-001
EINECS	Contact for details

Quality Control

Our 5-(3-(Benzyloxy)Phenyl)-5H-Pyrrolo[2,3-D]Pyrimidin-4-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your internal quality standards and regulatory requirements for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.