Description

(4-Bromo-2-Fluorophenylcarbamoyl)Methyl Acetate is a high-purity, advanced pharmaceutical intermediate and versatile chemical building block. This compound is critical for the synthesis of complex molecules, particularly in medicinal chemistry and agrochemical research, due to its reactive bromo and fluoro substituents. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries to develop new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its halogenated aromatic structure.
• Chemical Research & Development: Serves as a versatile precursor for Suzuki-Miyaura and other cross-coupling reactions to create complex biaryl structures.
• Material Science: Potential monomer or additive in the development of specialty polymers and advanced organic materials.
• Ligand and Catalyst Development: Useful scaffold for creating novel ligands in asymmetric catalysis and organometallic chemistry.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up campaigns.

Basic Information

Product Name	(4-Bromo-2-Fluorophenylcarbamoyl)Methyl Acetate
CAS No.	474806-63-8
Molecular Formula	C10H9BrFNO3
Molecular Weight	290.09 g/mol
Synonyms	Acetic acid, 2-[[(4-bromo-2-fluorophenyl)amino]carbonyl]methyl ester; 2-((4-Bromo-2-fluorophenyl)carbamoyl)methyl acetate; N-(4-Bromo-2-fluorophenyl)-2-(acetyloxy)acetamide; (4-Bromo-2-fluorophenylcarbamoyl)methyl acetate; Glycine, N-(4-bromo-2-fluorophenyl)-, 2-acetyl ester; Acetoxyacetic acid (4-bromo-2-fluoroanilide)
EINECS	Contact for details

Quality Control

Our (4-Bromo-2-Fluorophenylcarbamoyl)Methyl Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified for long-term storage. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.