Description

6-(4-(Allyloxy)Phenyl)-4-Hydroxy-5-(Thiophene-2-Carbonyl)-4-(Trifluoromethyl)Tetrahydropyrimidin-2(1H)-One is a sophisticated heterocyclic compound featuring a tetrahydropyrimidin-2(1H)-one core, strategically functionalized with trifluoromethyl, allyloxy phenyl, and thiophene carbonyl groups. This unique molecular architecture makes it a high-value intermediate for advanced research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents and crop protection solutions.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Serves as a precursor for developing new-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiophene and trifluoromethyl groups.
• Material Science: Potential monomer or additive for creating specialty polymers with unique optical or electronic properties.
• Chemical Biology Probe: Used in academic and industrial research to study enzyme inhibition and other biological pathways.
• Organic Synthesis Scaffold: Employed by medicinal chemists for parallel synthesis and library development to explore new chemical spaces.

Basic Information

Item	Detail
Product Name	6-(4-(Allyloxy)Phenyl)-4-Hydroxy-5-(Thiophene-2-Carbonyl)-4-(Trifluoromethyl)Tetrahydropyrimidin-2(1H)-One
CAS No.	474257-40-4
Molecular Formula	C20H17F3N2O4S
Molecular Weight	438.42 g/mol
Synonyms	4-Hydroxy-4-(trifluoromethyl)-6-[4-(2-propen-1-yloxy)phenyl]-5-(2-thienylcarbonyl)-1,4,5,6-tetrahydro-2(1H)-pyrimidinone; 4-Hydroxy-4-(trifluoromethyl)-6-[4-(allyloxy)phenyl]-5-(2-thiophenecarbonyl)-1,4,5,6-tetrahydro-2(1H)-pyrimidinone; 6-(4-Allyloxyphenyl)-4-hydroxy-5-(thiophene-2-carbonyl)-4-(trifluoromethyl)-1,4,5,6-tetrahydropyrimidin-2(1H)-one; CAS 474257-40-4
EINECS	Contact for details

Quality Control

Our production of 6-(4-(Allyloxy)Phenyl)-4-Hydroxy-5-(Thiophene-2-Carbonyl)-4-(Trifluoromethyl)Tetrahydropyrimidin-2(1H)-One adheres to stringent quality protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets exacting R&D and cGMP-grade standards. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere when not in use to prevent degradation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.