Description

2,5-Anhydro-3-Deoxy-3-(3,4-Dihydro-5-Methyl-2,4-Dioxo-1(2H)-Pyrimidinyl)-1-o-2-Propen-1-Yl-L-Mannitol is a sophisticated nucleoside analog derivative, representing a key intermediate in advanced pharmaceutical synthesis. This compound is valued for its role in the development of novel antiviral and anticancer therapeutics, where precise molecular structure is critical for biological activity. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the synthesis of modified nucleosides and nucleotide-based drugs.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to nucleotide metabolism and DNA/RNA synthesis pathways.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Process Development: Employed in scaling up and optimizing synthetic routes for active pharmaceutical ingredients (APIs) in GMP environments.
• Reference Standard: Used as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Item	Details
Product Name	2,5-Anhydro-3-Deoxy-3-(3,4-Dihydro-5-Methyl-2,4-Dioxo-1(2H)-Pyrimidinyl)-1-o-2-Propen-1-Yl-L-Mannitol
CAS No.	473796-98-4
Molecular Formula	C14H18N2O7
Molecular Weight	326.30 g/mol
Synonyms	1-O-Allyl-2,5-anhydro-3-deoxy-3-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-L-mannitol; 3'-Deoxy-3'-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-1'-O-allyl-L-mannitol; Allyl 3-deoxy-3-(5-methyluracil-1-yl)-2,5-anhydro-L-mannofuranoside; Nucleoside Mannitol Derivative; L-Mannitol, 2,5-anhydro-3-deoxy-3-(3,4-dihydro-5-methyl-2,4-dioxo-1(2H)-pyrimidinyl)-1-O-2-propen-1-yl-
EINECS	Contact for details

Quality Control

Our 2,5-Anhydro-3-Deoxy-3-(3,4-Dihydro-5-Methyl-2,4-Dioxo-1(2H)-Pyrimidinyl)-1-o-2-Propen-1-Yl-L-Mannitol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed in a desiccated environment away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.