Description

(1R)-1-(3-Fluorophenyl)-2,2-Dimethylpropan-1-Amine is a chiral amine building block of significant interest in advanced organic synthesis. This compound matters because its unique structure, featuring a fluorinated aromatic ring and a sterically hindered amine, makes it a valuable intermediate for creating complex molecules with tailored properties. Pharmaceutical and agrochemical research and development teams need it for the synthesis of potential active ingredients, where the fluorine atom and specific stereochemistry are critical for biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and metabolic disorder therapeutics.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides, where the fluorine moiety enhances lipophilicity and target binding.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic materials requiring fluorinated aromatic components.
• Chemical Biology Probes: Utilized as a building block for fluorescent tags and molecular probes in diagnostic and biochemical research.

Basic Information

Product Name	(1R)-1-(3-Fluorophenyl)-2,2-Dimethylpropan-1-Amine
CAS No.	473733-21-0
Molecular Formula	C11H16FN
Molecular Weight	181.25 g/mol
Synonyms	(R)-1-(3-Fluorophenyl)-2,2-dimethylpropan-1-amine; (1R)-1-(3-Fluorophenyl)-2,2-dimethyl-1-propanamine; (R)-α,α-Dimethyl-3-fluorobenzeneethanamine; (R)-3-Fluoro-α,α-dimethylbenzenemethanamine; (R)-1-(3-Fluorophenyl)-2-methyl-2-propylamine; (R)-3-Fluoro-α,α-dimethylbenzylamine; (R)-F-DMPA; (R)-F-DMBA
EINECS	Contact for details

Quality Control

Our (1R)-1-(3-Fluorophenyl)-2,2-Dimethylpropan-1-Amine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity determination by HPLC, to ensure compliance with exacting standards for research and development use. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.