Description

(1R)-1-(3-Fluorophenyl)-2-Methylpropylamine is a chiral amine building block of significant interest in advanced organic synthesis. Its value lies in its specific stereochemistry and fluorinated aromatic ring, which are crucial for modulating the biological activity and physicochemical properties of target molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) targets.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the fluorophenyl moiety enhances lipophilicity and metabolic stability.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands used in asymmetric catalysis, enabling the synthesis of enantiomerically pure compounds.
• Chemical Biology Research: Employed as a molecular probe or building block in medicinal chemistry for structure-activity relationship (SAR) studies.
• Fine Chemical Production: Integral to the multi-step synthesis of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	(1R)-1-(3-Fluorophenyl)-2-Methylpropylamine
CAS No.	473733-18-5
Molecular Formula	C10H14FN
Molecular Weight	167.22 g/mol
Synonyms	(R)-1-(3-Fluorophenyl)-2-methylpropan-1-amine; (1R)-1-(3-Fluorophenyl)-2-methylpropylamine; (R)-α-Methyl-3-fluorobenzeneethanamine; (R)-3-Fluoro-α-methylbenzenemethanamine; (R)-1-(3-Fluorophenyl)-2-methyl-1-propylamine; (R)-1-(3-Fluorophenyl)-2-methylpropylamine; (R)-3-Fluoro-α-methylbenzylamine; (R)-3-Fluoroamphetamine
EINECS	Contact for details

Quality Control

Our (1R)-1-(3-Fluorophenyl)-2-Methylpropylamine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.